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Symposium on aHUS in 2022

The twice delayed ISN Frontiers Symposium on Complement related renal diseases - MPGN/C3G and aHUS is still on course to be held in Bergamo, Italy on 23rd to 25th June…

Questions about aHUS triggers

It is known that certain rare genetic variants, mutations, or markers, in components of the Complement System make some people susceptible to aHUS. it is less known that there are…

Incomplete aHUS penetrance in families

Although aHUS has genetic causes, in the majority of cases it is found that the patient is the only one in the family with the genetic susceptibility for aHUS. That…

Hormones and aHUS

Questions about hormones and aHUS in the RDD2022 video. It is a feature of aHUS that it becomes more common in females after puberty and during pregnancy. Both puberty and…

aHUS remission chance and relapse risk

Remission from aHUS is different from having been cured because there is still an uncertainty that aHUS can return. If that happens it is called a relapse. For a relapse…

Atypical HUS PROs: Patient Reported Outcomes

What are patient reported outcomes (PROS)? The aHUS Alliance Global Action team look at PROs and their importance in the aHUS space.

Atypical HUS PROs

Who, or what, are atypical HUS PROs: are these people, concepts, or initiatives? In medical terminology PRO stands for ‘Patient Reported Outcomes’ and refers to comments made directly and in…

What would stop eculizumab working for aHUS?

Eculizumab was approved by the US Food and Drugs Administration for PNH for 15 years ago on 16 March. This September coming, it will be 11 years since the FDA…