aHUS Trials Watch

The aHUS trial scene is very active but aHUS patients are often unaware of what is happening. The aHUS alliance will therefore be keeping a watch and periodically report on current trials relating to aHUS ,both Primary and Secondary, to improve awareness.
As at the end of May 2017 the following trials are about to be active or are already recruiting , albeit there may be limitations on who may participate.
Click on each link to learn more the trials.

Available OMS721 Compassionate Use in Patients With Thrombotic Microangiopathy

Condition: Thrombotic Microangiopathy
Intervention: Biological: OMS721

 

Recruiting Safety and Efficacy Study of OMS721 in Patients With Thrombotic Microangiopathies

Condition: Thrombotic Microangiopathies
Intervention: Biological: OMS721

 

Not yet recruiting Study of ALXN1210 in Children and Adolescents With Atypical Hemolytic Uremic Syndrome (aHUS)

Condition: Atypical Hemolytic Uremic Syndrome (aHUS)
Intervention: Biological: ALXN1210

 

Recruiting Single Arm Study of ALXN1210 in Complement Inhibitor Treatment-Naïve Adult and Adolescent Patients With Atypical Hemolytic Uremic Syndrome (aHUS)

Condition: Atypical Hemolytic Uremic Syndrome (aHUS)
Intervention: Biological: ALXN1210

 

Recruiting Atypcial Hemolytic-Uremic Syndrome (aHUS) Registry

Condition: Atypical Hemolytic-Uremic Syndrome
Intervention:

 

Recruiting Study Assessing an Algorithm-based Strategy of Eculizumab Discontinuation in Children and Adults With aHUS (STOPECU)

Condition: Atypical Hemolytic Uremic Syndrome
Intervention: Drug: eculizumab

 

Enrolling by invitation Eval. of Potential Predictors of Disease Progression in Patients With aHUS Including Genetics, Biomarkers and Treatment (EVIDENCE)

Condition: Atypical Hemolytic Uremic Syndrome
Intervention: Other: Clinical assessments and laboratory tests.

 

Recruiting Identification and Treatment of Thrombotic Microangiopathies in Allogeneic Stem Cell Transplants

Conditions: Thrombotic Microangiopathy;   Disorder Related to Bone Marrow Transplantation
Intervention: Drug: eculizumab

 

Recruiting Eculizumab in Shiga-toxin Related Hemolytic and Uremic Syndrome Pediatric Patients – ECULISHU

Condition: Hemolytic Uremic Syndrome of Childhood
Interventions: Drug: Eculizumab;   Drug: Placebo

Leave a Reply